@prefix fhir: <http://hl7.org/fhir/> .
@prefix loinc: <http://loinc.org/rdf#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix sct: <http://snomed.info/id/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

# - resource -------------------------------------------------------------------

<http://hl7.org/fhir/Observation/f205> a fhir:Observation;
  fhir:nodeRole fhir:treeRoot;
  fhir:Resource.id [ fhir:value "f205"];
  fhir:DomainResource.text [
     fhir:Narrative.status [ fhir:value "generated" ];
     fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative</b></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource &quot;f205&quot; </p></div><p><b>identifier</b>: id: 1304-03720-eGFR</p><p><b>status</b>: final</p><p><b>code</b>: Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum or Plasma by Creatinine-based formula (MDRD) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#33914-3)</span></p><p><b>subject</b>: <a href=\"patient-f201.html\">Patient/f201: Roel</a> &quot;Roel&quot;</p><p><b>issued</b>: 05/04/2013 12:34:00 AM</p><p><b>performer</b>: <a href=\"practitioner-f202.html\">Practitioner/f202: Luigi Maas</a> &quot;Luigi Maas&quot;</p><p><b>interpretation</b>: interpretation of results should be assigned based upon the level of kindey function <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>note</b>: GFR estimating equations developed by the Modification of Diet in Renal Disease (MDRD) Study Group and the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI)....</p><p><b>method</b>: MDRD <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOMED CT</a>#702668005)</span></p><blockquote><p><b>component</b></p><p><b>code</b>: Glomerular filtration rate/1.73 sq M predicted among blacks [Volume Rate/?Area] in Serum or Plasma by Creatinine-based formula (MDRD) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#48643-1)</span></p><p><b>value</b>: &gt;60 mL/min/1.73m2<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code mL/min/{1.73_m2} = 'mL/min/{1.73_m2}')</span></p><h3>ReferenceRanges</h3><table class=\"grid\"><tr><td>-</td><td><b>Low</b></td><td><b>AppliesTo</b></td><td><b>Age</b></td></tr><tr><td>*</td><td>60 mL/min/1.73m2<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code mL/min/{1.73_m2} = 'mL/min/{1.73_m2}')</span></td><td>non-black/african-american <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td>18-? yrs</td></tr></table></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Glomerular filtration rate/1.73 sq M predicted among non-blacks [Volume Rate/Area] in Serum or Plasma by Creatinine-based formula (MDRD) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#48642-3)</span></p><p><b>value</b>: 60 mL/min/1.73m2<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code mL/min/{1.73_m2} = 'mL/min/{1.73_m2}')</span></p><h3>ReferenceRanges</h3><table class=\"grid\"><tr><td>-</td><td><b>Low</b></td><td><b>Age</b></td></tr><tr><td>*</td><td>60 mL/min/1.73m2<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code mL/min/{1.73_m2} = 'mL/min/{1.73_m2}')</span></td><td>18-? yrs</td></tr></table></blockquote></div>"
  ];
  fhir:Observation.identifier [
     fhir:index 0;
     fhir:Identifier.system [ fhir:value "https://intranet.aumc.nl/labvalues" ];
     fhir:Identifier.value [ fhir:value "1304-03720-eGFR" ]
  ];
  fhir:Observation.status [ fhir:value "final"];
  fhir:Observation.code [
     fhir:CodeableConcept.coding [
       fhir:index 0;
       a loinc:33914-3;
       fhir:Coding.system [ fhir:value "http://loinc.org" ];
       fhir:Coding.code [ fhir:value "33914-3" ];
       fhir:Coding.display [ fhir:value "Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum or Plasma by Creatinine-based formula (MDRD)" ]
     ]
  ];
  fhir:Observation.subject [
     fhir:link <http://hl7.org/fhir/Patient/f201>;
     fhir:Reference.reference [ fhir:value "Patient/f201" ];
     fhir:Reference.display [ fhir:value "Roel" ]
  ];
  fhir:Observation.issued [ fhir:value "2013-04-04T14:34:00+01:00"^^xsd:dateTime];
  fhir:Observation.performer [
     fhir:index 0;
     fhir:link <http://hl7.org/fhir/Practitioner/f202>;
     fhir:Reference.reference [ fhir:value "Practitioner/f202" ];
     fhir:Reference.display [ fhir:value "Luigi Maas" ]
  ];
  fhir:Observation.interpretation [
     fhir:index 0;
     fhir:CodeableConcept.text [ fhir:value "interpretation of results should be assigned based upon the level of kindey function" ]
  ];
  fhir:Observation.note [
     fhir:index 0;
     fhir:Annotation.text [ fhir:value "GFR estimating equations developed by the Modification of Diet in Renal Disease (MDRD) Study Group and the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI)...." ]
  ];
  fhir:Observation.method [
     fhir:CodeableConcept.coding [
       fhir:index 0;
       a sct:702668005;
       fhir:Coding.system [ fhir:value "http://snomed.info/sct" ];
       fhir:Coding.code [ fhir:value "702668005" ];
       fhir:Coding.display [ fhir:value "MDRD" ]
     ]
  ];
  fhir:Observation.component [
     fhir:index 0;
     fhir:Observation.component.code [
       fhir:CodeableConcept.coding [
         fhir:index 0;
         a loinc:48643-1;
         fhir:Coding.system [ fhir:value "http://loinc.org" ];
         fhir:Coding.code [ fhir:value "48643-1" ];
         fhir:Coding.display [ fhir:value "Glomerular filtration rate/1.73 sq M predicted among blacks [Volume Rate/?Area] in Serum or Plasma by Creatinine-based formula (MDRD)" ]
       ]
     ];
     fhir:Observation.component.valueQuantity [
       fhir:Quantity.value [ fhir:value "60"^^xsd:decimal ];
       fhir:Quantity.comparator [ fhir:value ">" ];
       fhir:Quantity.unit [ fhir:value "mL/min/1.73m2" ];
       fhir:Quantity.system [ fhir:value "http://unitsofmeasure.org" ];
       fhir:Quantity.code [ fhir:value "mL/min/{1.73_m2}" ]
     ];
     fhir:Observation.component.referenceRange [
       fhir:index 0;
       fhir:Observation.referenceRange.low [
         fhir:Quantity.value [ fhir:value "60"^^xsd:decimal ];
         fhir:Quantity.unit [ fhir:value "mL/min/1.73m2" ];
         fhir:Quantity.system [ fhir:value "http://unitsofmeasure.org" ];
         fhir:Quantity.code [ fhir:value "mL/min/{1.73_m2}" ]
       ];
       fhir:Observation.referenceRange.appliesTo [
         fhir:index 0;
         fhir:CodeableConcept.text [ fhir:value "non-black/african-american" ]
       ];
       fhir:Observation.referenceRange.age [
         fhir:Range.low [
           fhir:Quantity.value [ fhir:value "18"^^xsd:decimal ];
           fhir:Quantity.unit [ fhir:value "yrs" ];
           fhir:Quantity.system [ fhir:value "http://unitsofmeasure.org" ];
           fhir:Quantity.code [ fhir:value "a" ]
         ]
       ]
     ]
  ], [
     fhir:index 1;
     fhir:Observation.component.code [
       fhir:CodeableConcept.coding [
         fhir:index 0;
         a loinc:48642-3;
         fhir:Coding.system [ fhir:value "http://loinc.org" ];
         fhir:Coding.code [ fhir:value "48642-3" ];
         fhir:Coding.display [ fhir:value "Glomerular filtration rate/1.73 sq M predicted among non-blacks [Volume Rate/Area] in Serum or Plasma by Creatinine-based formula (MDRD)" ]
       ]
     ];
     fhir:Observation.component.valueQuantity [
       fhir:Quantity.value [ fhir:value "60"^^xsd:decimal ];
       fhir:Quantity.unit [ fhir:value "mL/min/1.73m2" ];
       fhir:Quantity.system [ fhir:value "http://unitsofmeasure.org" ];
       fhir:Quantity.code [ fhir:value "mL/min/{1.73_m2}" ]
     ];
     fhir:Observation.component.referenceRange [
       fhir:index 0;
       fhir:Observation.referenceRange.low [
         fhir:Quantity.value [ fhir:value "60"^^xsd:decimal ];
         fhir:Quantity.unit [ fhir:value "mL/min/1.73m2" ];
         fhir:Quantity.system [ fhir:value "http://unitsofmeasure.org" ];
         fhir:Quantity.code [ fhir:value "mL/min/{1.73_m2}" ]
       ];
       fhir:Observation.referenceRange.age [
         fhir:Range.low [
           fhir:Quantity.value [ fhir:value "18"^^xsd:decimal ];
           fhir:Quantity.unit [ fhir:value "yrs" ];
           fhir:Quantity.system [ fhir:value "http://unitsofmeasure.org" ];
           fhir:Quantity.code [ fhir:value "a" ]
         ]
       ]
     ]
  ] .

<http://hl7.org/fhir/Patient/f201> a fhir:Patient .

<http://hl7.org/fhir/Practitioner/f202> a fhir:Practitioner .

# - ontology header ------------------------------------------------------------

<http://hl7.org/fhir/Observation/f205.ttl> a owl:Ontology;
  owl:imports fhir:fhir.ttl;
  owl:versionIRI <http://build.fhir.org/Observation/f205.ttl> .

# -------------------------------------------------------------------------------------