PREFIX fhir: <http://hl7.org/fhir/> 
PREFIX fhirvs: <http://hl7.org/fhir/ValueSet/>
PREFIX xsd: <http://www.w3.org/2001/XMLSchema#> 
BASE <http://hl7.org/fhir/shape/>


start=@<MolecularSequence> AND {fhir:nodeRole [fhir:treeRoot]}


# Information about a biological sequence
<MolecularSequence> CLOSED {

    a [fhir:MolecularSequence];
    fhir:nodeRole [fhir:treeRoot]?;
    fhir:Resource.id id?;                   # Logical id of this artifact
    fhir:Resource.meta @<Meta>?;            # Metadata about the resource
    fhir:Resource.implicitRules @<uri>?;    # A set of rules under which this 
                                            # content was created 
    fhir:Resource.language @<code>?;        # Language of the resource content
    fhir:DomainResource.text @<Narrative>?;  # Text summary of the resource, for 
                                            # human interpretation 
    fhir:DomainResource.contained @<Resource>*;  # Contained, inline Resources
    fhir:DomainResource.extension @<Extension>*;  # Additional content defined by 
                                            # implementations 
    fhir:DomainResource.modifierExtension @<Extension>*;  # Extensions that cannot be ignored
    fhir:MolecularSequence.identifier @<Identifier>*;  # Unique ID for this particular 
                                            # sequence. This is a FHIR-defined 
                                            # id 
    fhir:MolecularSequence.type @<code> AND
    	{fhir:value @fhirvs:sequence-type}?;  # aa | dna | rna
    fhir:MolecularSequence.coordinateSystem @<integer>;  # Base number of coordinate system 
                                            # (0 for 0-based numbering or 
                                            # coordinates, inclusive start, 
                                            # exclusive end, 1 for 1-based 
                                            # numbering, inclusive start, 
                                            # inclusive end) 
    fhir:MolecularSequence.patient @<Reference>?;  # Who and/or what this is about
    fhir:MolecularSequence.specimen @<Reference>?;  # Specimen used for sequencing
    fhir:MolecularSequence.device @<Reference>?;  # The method for sequencing
    fhir:MolecularSequence.performer @<Reference>?;  # Who should be responsible for test 
                                            # result 
    fhir:MolecularSequence.quantity @<Quantity>?;  # The number of copies of the 
                                            # sequence of interest.  (RNASeq) 
    fhir:MolecularSequence.referenceSeq @<MolecularSequence.referenceSeq>?;  # A sequence used as reference
    fhir:MolecularSequence.variant @<MolecularSequence.variant>*;  # Variant in sequence
    fhir:MolecularSequence.observedSeq @<string>?;  # Sequence that was observed
    fhir:MolecularSequence.quality @<MolecularSequence.quality>*;  # An set of value as quality of 
                                            # sequence 
    fhir:MolecularSequence.readCoverage @<integer>?;  # Average number of reads 
                                            # representing a given nucleotide in 
                                            # the reconstructed sequence 
    fhir:MolecularSequence.repository @<MolecularSequence.repository>*;  # External repository which contains 
                                            # detailed report related with 
                                            # observedSeq in this resource 
    fhir:MolecularSequence.pointer @<Reference>*;  # Pointer to next atomic sequence
    fhir:MolecularSequence.structureVariant @<MolecularSequence.structureVariant>*;  # Structural variant
    fhir:index xsd:integer?                 # Relative position in a list
}

# Variant in sequence
<MolecularSequence.variant> CLOSED {
    fhir:Element.id string?;                # Unique id for inter-element 
                                            # referencing 
    fhir:Element.extension @<Extension>*;   # Additional content defined by 
                                            # implementations 
    fhir:BackboneElement.modifierExtension @<Extension>*;  # Extensions that cannot be ignored 
                                            # even if unrecognized 
    fhir:MolecularSequence.variant.start @<integer>?;  # Start position of the variant on 
                                            # the  reference sequence 
    fhir:MolecularSequence.variant.end @<integer>?;  # End position of the variant on the 
                                            # reference sequence 
    fhir:MolecularSequence.variant.observedAllele @<string>?;  # Allele that was observed
    fhir:MolecularSequence.variant.referenceAllele @<string>?;  # Allele in the reference sequence
    fhir:MolecularSequence.variant.cigar @<string>?;  # Extended CIGAR string for aligning 
                                            # the sequence with reference bases 
    fhir:MolecularSequence.variant.variantPointer @<Reference>?;  # Pointer to observed variant 
                                            # information 
    fhir:index xsd:integer?                 # Relative position in a list
}

# External repository which contains detailed report related with observedSeq in this resource
<MolecularSequence.repository> CLOSED {
    fhir:Element.id string?;                # Unique id for inter-element 
                                            # referencing 
    fhir:Element.extension @<Extension>*;   # Additional content defined by 
                                            # implementations 
    fhir:BackboneElement.modifierExtension @<Extension>*;  # Extensions that cannot be ignored 
                                            # even if unrecognized 
    fhir:MolecularSequence.repository.type @<code> AND
    	{fhir:value @fhirvs:repository-type};  # directlink | openapi | login | 
                                            # oauth | other 
    fhir:MolecularSequence.repository.url @<uri>?;  # URI of the repository
    fhir:MolecularSequence.repository.name @<string>?;  # Repository's name
    fhir:MolecularSequence.repository.datasetId @<string>?;  # Id of the dataset that used to 
                                            # call for dataset in repository 
    fhir:MolecularSequence.repository.variantsetId @<string>?;  # Id of the variantset that used to 
                                            # call for variantset in repository 
    fhir:MolecularSequence.repository.readsetId @<string>?;  # Id of the read
    fhir:index xsd:integer?                 # Relative position in a list
}

# Structural variant
<MolecularSequence.structureVariant> CLOSED {
    fhir:Element.id string?;                # Unique id for inter-element 
                                            # referencing 
    fhir:Element.extension @<Extension>*;   # Additional content defined by 
                                            # implementations 
    fhir:BackboneElement.modifierExtension @<Extension>*;  # Extensions that cannot be ignored 
                                            # even if unrecognized 
    fhir:MolecularSequence.structureVariant.variantType @<CodeableConcept>?;  # Structural variant change type
    fhir:MolecularSequence.structureVariant.exact @<boolean>?;  # Does the structural variant have 
                                            # base pair resolution breakpoints? 
    fhir:MolecularSequence.structureVariant.length @<integer>?;  # Structural variant length
    fhir:MolecularSequence.structureVariant.outer @<MolecularSequence.structureVariant.outer>?;  # Structural variant outer
    fhir:MolecularSequence.structureVariant.inner @<MolecularSequence.structureVariant.inner>?;  # Structural variant inner
    fhir:index xsd:integer?                 # Relative position in a list
}

# An set of value as quality of sequence
<MolecularSequence.quality> CLOSED {
    fhir:Element.id string?;                # Unique id for inter-element 
                                            # referencing 
    fhir:Element.extension @<Extension>*;   # Additional content defined by 
                                            # implementations 
    fhir:BackboneElement.modifierExtension @<Extension>*;  # Extensions that cannot be ignored 
                                            # even if unrecognized 
    fhir:MolecularSequence.quality.type @<code> AND
    	{fhir:value @fhirvs:quality-type};  # indel | snp | unknown
    fhir:MolecularSequence.quality.standardSequence @<CodeableConcept>?;  # Standard sequence for comparison
    fhir:MolecularSequence.quality.start @<integer>?;  # Start position of the sequence
    fhir:MolecularSequence.quality.end @<integer>?;  # End position of the sequence
    fhir:MolecularSequence.quality.score @<Quantity>?;  # Quality score for the comparison
    fhir:MolecularSequence.quality.method @<CodeableConcept>?;  # Method to get quality
    fhir:MolecularSequence.quality.truthTP @<decimal>?;  # True positives from the 
                                            # perspective of the truth data 
    fhir:MolecularSequence.quality.queryTP @<decimal>?;  # True positives from the 
                                            # perspective of the query data 
    fhir:MolecularSequence.quality.truthFN @<decimal>?;  # False negatives
    fhir:MolecularSequence.quality.queryFP @<decimal>?;  # False positives
    fhir:MolecularSequence.quality.gtFP @<decimal>?;  # False positives where the non-REF 
                                            # alleles in the Truth and Query 
                                            # Call Sets match 
    fhir:MolecularSequence.quality.precision @<decimal>?;  # Precision of comparison
    fhir:MolecularSequence.quality.recall @<decimal>?;  # Recall of comparison
    fhir:MolecularSequence.quality.fScore @<decimal>?;  # F-score
    fhir:MolecularSequence.quality.roc @<MolecularSequence.quality.roc>?;  # Receiver Operator Characteristic 
                                            # (ROC) Curve 
    fhir:index xsd:integer?                 # Relative position in a list
}

# A sequence used as reference
<MolecularSequence.referenceSeq> CLOSED {
    fhir:Element.id string?;                # Unique id for inter-element 
                                            # referencing 
    fhir:Element.extension @<Extension>*;   # Additional content defined by 
                                            # implementations 
    fhir:BackboneElement.modifierExtension @<Extension>*;  # Extensions that cannot be ignored 
                                            # even if unrecognized 
    fhir:MolecularSequence.referenceSeq.chromosome @<CodeableConcept>?;  # Chromosome containing genetic 
                                            # finding 
    fhir:MolecularSequence.referenceSeq.genomeBuild @<string>?;  # The Genome Build used for 
                                            # reference, following GRCh build 
                                            # versions e.g. 'GRCh 37' 
    fhir:MolecularSequence.referenceSeq.orientation @<code> AND
    	{fhir:value @fhirvs:orientation-type}?;  # sense | antisense
    fhir:MolecularSequence.referenceSeq.referenceSeqId @<CodeableConcept>?;  # Reference identifier
    fhir:MolecularSequence.referenceSeq.referenceSeqPointer @<Reference>?;  # A pointer to another 
                                            # MolecularSequence entity as 
                                            # reference sequence 
    fhir:MolecularSequence.referenceSeq.referenceSeqString @<string>?;  # A string to represent reference 
                                            # sequence 
    fhir:MolecularSequence.referenceSeq.strand @<code> AND
    	{fhir:value @fhirvs:strand-type}?;  # watson | crick
    fhir:MolecularSequence.referenceSeq.windowStart @<integer>?;  # Start position of the window on 
                                            # the  reference sequence 
    fhir:MolecularSequence.referenceSeq.windowEnd @<integer>?;  # End position of the window on the 
                                            # reference sequence 
    fhir:index xsd:integer?                 # Relative position in a list
}

# Structural variant inner
<MolecularSequence.structureVariant.inner> CLOSED {
    fhir:Element.id string?;                # Unique id for inter-element 
                                            # referencing 
    fhir:Element.extension @<Extension>*;   # Additional content defined by 
                                            # implementations 
    fhir:BackboneElement.modifierExtension @<Extension>*;  # Extensions that cannot be ignored 
                                            # even if unrecognized 
    fhir:MolecularSequence.structureVariant.inner.start @<integer>?;  # Structural variant inner start
    fhir:MolecularSequence.structureVariant.inner.end @<integer>?;  # Structural variant inner end
    fhir:index xsd:integer?                 # Relative position in a list
}

# Receiver Operator Characteristic (ROC) Curve
<MolecularSequence.quality.roc> CLOSED {
    fhir:Element.id string?;                # Unique id for inter-element 
                                            # referencing 
    fhir:Element.extension @<Extension>*;   # Additional content defined by 
                                            # implementations 
    fhir:BackboneElement.modifierExtension @<Extension>*;  # Extensions that cannot be ignored 
                                            # even if unrecognized 
    fhir:MolecularSequence.quality.roc.score @<integer>*;  # Genotype quality score
    fhir:MolecularSequence.quality.roc.numTP @<integer>*;  # Roc score true positive numbers
    fhir:MolecularSequence.quality.roc.numFP @<integer>*;  # Roc score false positive numbers
    fhir:MolecularSequence.quality.roc.numFN @<integer>*;  # Roc score false negative numbers
    fhir:MolecularSequence.quality.roc.precision @<decimal>*;  # Precision of the GQ score
    fhir:MolecularSequence.quality.roc.sensitivity @<decimal>*;  # Sensitivity of the GQ score
    fhir:MolecularSequence.quality.roc.fMeasure @<decimal>*;  # FScore of the GQ score
    fhir:index xsd:integer?                 # Relative position in a list
}

# Structural variant outer
<MolecularSequence.structureVariant.outer> CLOSED {
    fhir:Element.id string?;                # Unique id for inter-element 
                                            # referencing 
    fhir:Element.extension @<Extension>*;   # Additional content defined by 
                                            # implementations 
    fhir:BackboneElement.modifierExtension @<Extension>*;  # Extensions that cannot be ignored 
                                            # even if unrecognized 
    fhir:MolecularSequence.structureVariant.outer.start @<integer>?;  # Structural variant outer start
    fhir:MolecularSequence.structureVariant.outer.end @<integer>?;  # Structural variant outer end
    fhir:index xsd:integer?                 # Relative position in a list
}

#---------------------- Data Types -------------------

# Metadata about a resource
<Meta> CLOSED {
    fhir:Element.id id?;                    # Unique id for inter-element 
                                            # referencing 
    fhir:Element.extension @<Extension>*;   # Additional content defined by 
                                            # implementations 
    fhir:Meta.versionId @<id>?;             # Version specific identifier
    fhir:Meta.lastUpdated @<instant>?;      # When the resource version last 
                                            # changed 
    fhir:Meta.source @<uri>?;               # Identifies where the resource 
                                            # comes from 
    fhir:Meta.profile @<canonical>*;        # Profiles this resource claims to 
                                            # conform to 
    fhir:Meta.security @<Coding>*;          # Security Labels applied to this 
                                            # resource 
    fhir:Meta.tag @<Coding>*;               # Tags applied to this resource
    fhir:index xsd:integer?                 # Relative position in a list
}

# Primitive Type code
<code> CLOSED {
    fhir:Element.id string?;                # xml:id (or equivalent in JSON)
    fhir:Element.extension @<Extension>*;   # Additional content defined by 
                                            # implementations 
    fhir:value code?;                       # Primitive value for code
    fhir:index xsd:integer?                 # Relative position in a list
}

# Primitive Type string
<string> CLOSED {
    fhir:Element.id string?;                # xml:id (or equivalent in JSON)
    fhir:Element.extension @<Extension>*;   # Additional content defined by 
                                            # implementations 
    fhir:value string MAXLENGTH 1048576?;   # Primitive value for string
    fhir:index xsd:integer?                 # Relative position in a list
}

# A reference from one resource to another
<Reference> CLOSED {
    fhir:link IRI?;
    fhir:Element.id id?;                    # Unique id for inter-element 
                                            # referencing 
    fhir:Element.extension @<Extension>*;   # Additional content defined by 
                                            # implementations 
    fhir:Reference.reference @<string>?;    # Literal reference, Relative, 
                                            # internal or absolute URL 
    fhir:Reference.type @<uri>?;            # Type the reference refers to (e.g. 
                                            # "Patient") 
    fhir:Reference.identifier @<Identifier>?;  # Logical reference, when literal 
                                            # reference is not known 
    fhir:Reference.display @<string>?;      # Text alternative for the resource
    fhir:index xsd:integer?                 # Relative position in a list
}

# Base Resource
<Resource> {a .+;
    fhir:Resource.id id?;                   # Logical id of this artifact
    fhir:Resource.meta @<Meta>?;            # Metadata about the resource
    fhir:Resource.implicitRules @<uri>?;    # A set of rules under which this 
                                            # content was created 
    fhir:Resource.language @<code>?;        # Language of the resource content
    fhir:index xsd:integer?
}

# A measured or measurable amount
<Quantity> CLOSED {
    fhir:Element.id id?;                    # Unique id for inter-element 
                                            # referencing 
    fhir:Element.extension @<Extension>*;   # Additional content defined by 
                                            # implementations 
    fhir:Quantity.value @<decimal>?;        # Numerical value (with implicit 
                                            # precision) 
    fhir:Quantity.comparator @<code> AND
    	{fhir:value @fhirvs:quantity-comparator}?;  # < | <= | >= | > - how to 
                                            # understand the value 
    fhir:Quantity.unit @<string>?;          # Unit representation
    fhir:Quantity.system @<uri>?;           # System that defines coded unit form
    fhir:Quantity.code @<code>?;            # Coded form of the unit
    fhir:index xsd:integer?                 # Relative position in a list
}

# Primitive Type integer
<integer> CLOSED {
    fhir:Element.id string?;                # xml:id (or equivalent in JSON)
    fhir:Element.extension @<Extension>*;   # Additional content defined by 
                                            # implementations 
    fhir:value integer MININCLUSIVE -2147483648 MAXINCLUSIVE 2147483647?;  # Primitive value for integer
    fhir:index xsd:integer?                 # Relative position in a list
}

# Primitive Type uri
<uri> CLOSED {
    fhir:Element.id string?;                # xml:id (or equivalent in JSON)
    fhir:Element.extension @<Extension>*;   # Additional content defined by 
                                            # implementations 
    fhir:value uri?;                        # Primitive value for uri
    fhir:index xsd:integer?                 # Relative position in a list
}

# Optional Extensions Element
<Extension> CLOSED {
    fhir:Element.id id?; 
    fhir:Element.extension @<Extension>*; 
    fhir:Extension.url uri; 
    ( 
        fhir:Extension.valueBase64Binary @<base64Binary>  |
        fhir:Extension.valueBoolean @<boolean>  |
        fhir:Extension.valueCanonical @<canonical>  |
        fhir:Extension.valueCode @<code>  |
        fhir:Extension.valueDate @<date>  |
        fhir:Extension.valueDateTime @<dateTime>  |
        fhir:Extension.valueDecimal @<decimal>  |
        fhir:Extension.valueId @<id>  |
        fhir:Extension.valueInstant @<instant>  |
        fhir:Extension.valueInteger @<integer>  |
        fhir:Extension.valueMarkdown @<markdown>  |
        fhir:Extension.valueOid @<oid>  |
        fhir:Extension.valuePositiveInt @<positiveInt>  |
        fhir:Extension.valueString @<string>  |
        fhir:Extension.valueTime @<time>  |
        fhir:Extension.valueUnsignedInt @<unsignedInt>  |
        fhir:Extension.valueUri @<uri>  |
        fhir:Extension.valueUrl @<url>  |
        fhir:Extension.valueUuid @<uuid>  |
        fhir:Extension.valueAddress @<Address>  |
        fhir:Extension.valueAge @<Age>  |
        fhir:Extension.valueAnnotation @<Annotation>  |
        fhir:Extension.valueAttachment @<Attachment>  |
        fhir:Extension.valueCodeableConcept @<CodeableConcept>  |
        fhir:Extension.valueCodeableReference @<CodeableReference>  |
        fhir:Extension.valueCoding @<Coding>  |
        fhir:Extension.valueContactPoint @<ContactPoint>  |
        fhir:Extension.valueCount @<Count>  |
        fhir:Extension.valueDistance @<Distance>  |
        fhir:Extension.valueDuration @<Duration>  |
        fhir:Extension.valueHumanName @<HumanName>  |
        fhir:Extension.valueIdentifier @<Identifier>  |
        fhir:Extension.valueMoney @<Money>  |
        fhir:Extension.valuePeriod @<Period>  |
        fhir:Extension.valueQuantity @<Quantity>  |
        fhir:Extension.valueRange @<Range>  |
        fhir:Extension.valueRatio @<Ratio>  |
        fhir:Extension.valueRatioRange @<RatioRange>  |
        fhir:Extension.valueReference @<Reference>  |
        fhir:Extension.valueSampledData @<SampledData>  |
        fhir:Extension.valueSignature @<Signature>  |
        fhir:Extension.valueTiming @<Timing>  |
        fhir:Extension.valueContactDetail @<ContactDetail>  |
        fhir:Extension.valueContributor @<Contributor>  |
        fhir:Extension.valueDataRequirement @<DataRequirement>  |
        fhir:Extension.valueExpression @<Expression>  |
        fhir:Extension.valueParameterDefinition @<ParameterDefinition>  |
        fhir:Extension.valueRelatedArtifact @<RelatedArtifact>  |
        fhir:Extension.valueTriggerDefinition @<TriggerDefinition>  |
        fhir:Extension.valueUsageContext @<UsageContext>  |
        fhir:Extension.valueDosage @<Dosage> 
    )?;
    fhir:index xsd:integer?                 # Relative position in a list
}

# An identifier intended for computation
<Identifier> CLOSED {
    fhir:Element.id id?;                    # Unique id for inter-element 
                                            # referencing 
    fhir:Element.extension @<Extension>*;   # Additional content defined by 
                                            # implementations 
    fhir:Identifier.use @<code> AND
    	{fhir:value @fhirvs:identifier-use}?;  # usual | official | temp | 
                                            # secondary | old (If known) 
    fhir:Identifier.type @<CodeableConcept>?;  # Description of identifier
    fhir:Identifier.system @<uri>?;         # The namespace for the identifier 
                                            # value 
    fhir:Identifier.value @<string>?;       # The value that is unique
    fhir:Identifier.period @<Period>?;      # Time period when id is/was valid 
                                            # for use 
    fhir:Identifier.assigner @<Reference>?;  # Organization that issued id (may 
                                            # be just text) 
    fhir:index xsd:integer?                 # Relative position in a list
}

# Primitive Type boolean
<boolean> CLOSED {
    fhir:Element.id string?;                # xml:id (or equivalent in JSON)
    fhir:Element.extension @<Extension>*;   # Additional content defined by 
                                            # implementations 
    fhir:value boolean?;                    # Primitive value for boolean
    fhir:index xsd:integer?                 # Relative position in a list
}

# Human-readable summary of the resource (essential clinical and business information)
<Narrative> CLOSED {
    fhir:Element.id id?;                    # Unique id for inter-element 
                                            # referencing 
    fhir:Element.extension @<Extension>*;   # Additional content defined by 
                                            # implementations 
    fhir:Narrative.status @<code> AND
    	{fhir:value @fhirvs:narrative-status};  # generated | extensions | 
                                            # additional | empty 
    fhir:Narrative.div xsd:string;          # Limited xhtml content
    fhir:index xsd:integer?                 # Relative position in a list
}

# Primitive Type decimal
<decimal> CLOSED {
    fhir:Element.id string?;                # xml:id (or equivalent in JSON)
    fhir:Element.extension @<Extension>*;   # Additional content defined by 
                                            # implementations 
    fhir:value decimal?;                    # Primitive value for decimal
    fhir:index xsd:integer?                 # Relative position in a list
}

# Concept - reference to a terminology or just  text
<CodeableConcept> CLOSED {
    a NONLITERAL*;
    fhir:Element.id id?;                    # Unique id for inter-element 
                                            # referencing 
    fhir:Element.extension @<Extension>*;   # Additional content defined by 
                                            # implementations 
    fhir:CodeableConcept.coding @<Coding>*;  # Code defined by a terminology 
                                            # system 
    fhir:CodeableConcept.text @<string>?;   # Plain text representation of the 
                                            # concept 
    fhir:index xsd:integer?                 # Relative position in a list
}

# Primitive Type date
<date> CLOSED {
    fhir:Element.id string?;                # xml:id (or equivalent in JSON)
    fhir:Element.extension @<Extension>*;   # Additional content defined by 
                                            # implementations 
    fhir:value date?;                       # Primitive value for date
    fhir:index xsd:integer?                 # Relative position in a list
}

# An address expressed using postal conventions (as opposed to GPS or other location definition formats)
<Address> CLOSED {
    fhir:Element.id id?;                    # Unique id for inter-element 
                                            # referencing 
    fhir:Element.extension @<Extension>*;   # Additional content defined by 
                                            # implementations 
    fhir:Address.use @<code> AND
    	{fhir:value @fhirvs:address-use}?;  # home | work | temp | old | billing 
                                            # - purpose of this address 
    fhir:Address.type @<code> AND
    	{fhir:value @fhirvs:address-type}?;  # postal | physical | both
    fhir:Address.text @<string>?;           # Text representation of the address
    fhir:Address.line @<string>*;           # Street name, number, direction & 
                                            # P.O. Box etc. 
    fhir:Address.city @<string>?;           # Name of city, town etc.
    fhir:Address.district @<string>?;       # District name (aka county)
    fhir:Address.state @<string>?;          # Sub-unit of country (abbreviations 
                                            # ok) 
    fhir:Address.postalCode @<string>?;     # Postal code for area
    fhir:Address.country @<string>?;        # Country (e.g. can be ISO 3166 2 or 
                                            # 3 letter code) 
    fhir:Address.period @<Period>?;         # Time period when address was/is in 
                                            # use 
    fhir:index xsd:integer?                 # Relative position in a list
}

# Content in a format defined elsewhere
<Attachment> CLOSED {
    fhir:Element.id id?;                    # Unique id for inter-element 
                                            # referencing 
    fhir:Element.extension @<Extension>*;   # Additional content defined by 
                                            # implementations 
    fhir:Attachment.contentType @<code> AND
    	{fhir:value @fhirvs:mimetypes}?;  # Mime type of the content, with 
                                            # charset etc. 
    fhir:Attachment.language @<code>?;      # Human language of the content 
                                            # (BCP-47) 
    fhir:Attachment.data @<base64Binary>?;  # Data inline, base64ed
    fhir:Attachment.url @<url>?;            # Uri where the data can be found
    fhir:Attachment.size @<unsignedInt>?;   # Number of bytes of content (if url 
                                            # provided) 
    fhir:Attachment.hash @<base64Binary>?;  # Hash of the data (sha-1, base64ed)
    fhir:Attachment.title @<string>?;       # Label to display in place of the 
                                            # data 
    fhir:Attachment.creation @<dateTime>?;  # Date attachment was first created
    fhir:index xsd:integer?                 # Relative position in a list
}

# A measured or measurable amount
<Count> CLOSED {
    fhir:Element.id id?;                    # Unique id for inter-element 
                                            # referencing 
    fhir:Element.extension @<Extension>*;   # Additional content defined by 
                                            # implementations 
    fhir:Quantity.value @<decimal>?;        # Numerical value (with implicit 
                                            # precision) 
    fhir:Quantity.comparator @<code> AND
    	{fhir:value @fhirvs:quantity-comparator}?;  # < | <= | >= | > - how to 
                                            # understand the value 
    fhir:Quantity.unit @<string>?;          # Unit representation
    fhir:Quantity.system @<uri>?;           # System that defines coded unit form
    fhir:Quantity.code @<code>?;            # Coded form of the unit
    fhir:index xsd:integer?                 # Relative position in a list
}

# Describes a required data item
<DataRequirement> CLOSED {
    fhir:Element.id id?;                    # Unique id for inter-element 
                                            # referencing 
    fhir:Element.extension @<Extension>*;   # Additional content defined by 
                                            # implementations 
    fhir:DataRequirement.type @<code> AND
    	{fhir:value @fhirvs:all-types};  # The type of the required data
    fhir:DataRequirement.profile @<canonical>*;  # The profile of the required data
    (                                       # E.g. Patient, Practitioner, 
                                            # RelatedPerson, Organization, 
                                            # Location, Device 
        fhir:DataRequirement.subjectCodeableConcept @<CodeableConcept>  |
        fhir:DataRequirement.subjectReference @<Reference> 
    )?;
    fhir:DataRequirement.mustSupport @<string>*;  # Indicates specific structure 
                                            # elements that are referenced by 
                                            # the knowledge module 
    fhir:DataRequirement.codeFilter @<DataRequirement.codeFilter>*;  # What codes are expected
    fhir:DataRequirement.dateFilter @<DataRequirement.dateFilter>*;  # What dates/date ranges are expected
    fhir:DataRequirement.limit @<positiveInt>?;  # Number of results
    fhir:DataRequirement.sort @<DataRequirement.sort>*;  # Order of the results
    fhir:index xsd:integer?                 # Relative position in a list
}

# How the medication is/was taken or should be taken
<Dosage> CLOSED {
    fhir:Element.id id?;                    # Unique id for inter-element 
                                            # referencing 
    fhir:Element.extension @<Extension>*;   # Additional content defined by 
                                            # implementations 
    fhir:BackboneElement.modifierExtension @<Extension>*;  # Extensions that cannot be ignored 
                                            # even if unrecognized 
    fhir:Dosage.sequence @<integer>?;       # The order of the dosage 
                                            # instructions 
    fhir:Dosage.text @<string>?;            # Free text dosage instructions e.g. 
                                            # SIG 
    fhir:Dosage.additionalInstruction @<CodeableConcept>*;  # Supplemental instruction or 
                                            # warnings to the patient - e.g. 
                                            # "with meals", "may cause 
                                            # drowsiness" 
    fhir:Dosage.patientInstruction @<string>?;  # Patient or consumer oriented 
                                            # instructions 
    fhir:Dosage.timing @<Timing>?;          # When medication should be 
                                            # administered 
    (                                       # Take "as needed" (for x)
        fhir:Dosage.asNeededBoolean @<boolean>  |
        fhir:Dosage.asNeededCodeableConcept @<CodeableConcept> 
    )?;
    fhir:Dosage.site @<CodeableConcept>?;   # Body site to administer to
    fhir:Dosage.route @<CodeableConcept>?;  # How drug should enter body
    fhir:Dosage.method @<CodeableConcept>?;  # Technique for administering 
                                            # medication 
    fhir:Dosage.doseAndRate @<Dosage.doseAndRate>*;  # Amount of medication administered
    fhir:Dosage.maxDosePerPeriod @<Ratio>?;  # Upper limit on medication per unit 
                                            # of time 
    fhir:Dosage.maxDosePerAdministration @<SimpleQuantity>?;  # Upper limit on medication per 
                                            # administration 
    fhir:Dosage.maxDosePerLifetime @<SimpleQuantity>?;  # Upper limit on medication per 
                                            # lifetime of the patient 
    fhir:index xsd:integer?                 # Relative position in a list
}

# Primitive Type uuid
<uuid> CLOSED {
    fhir:Element.id string?;                # xml:id (or equivalent in JSON)
    fhir:Element.extension @<Extension>*;   # Additional content defined by 
                                            # implementations 
    fhir:value uuid?;                       # Primitive value for uuid
    fhir:index xsd:integer?                 # Relative position in a list
}

# Range of ratio values
<RatioRange> CLOSED {
    fhir:Element.id id?;                    # Unique id for inter-element 
                                            # referencing 
    fhir:Element.extension @<Extension>*;   # Additional content defined by 
                                            # implementations 
    fhir:RatioRange.lowNumerator @<SimpleQuantity>?;  # Low Numerator limit
    fhir:RatioRange.highNumerator @<SimpleQuantity>?;  # High Numerator limit
    fhir:RatioRange.denominator @<SimpleQuantity>?;  # Denominator value
    fhir:index xsd:integer?                 # Relative position in a list
}

# A reference to a code defined by a terminology system
<Coding> CLOSED {
    a NONLITERAL?;
    fhir:Element.id id?;                    # Unique id for inter-element 
                                            # referencing 
    fhir:Element.extension @<Extension>*;   # Additional content defined by 
                                            # implementations 
    fhir:Coding.system @<uri>?;             # Identity of the terminology system
    fhir:Coding.version @<string>?;         # Version of the system - if relevant
    fhir:Coding.code @<code>?;              # Symbol in syntax defined by the 
                                            # system 
    fhir:Coding.display @<string>?;         # Representation defined by the 
                                            # system 
    fhir:Coding.userSelected @<boolean>?;   # If this coding was chosen directly 
                                            # by the user 
    fhir:index xsd:integer?                 # Relative position in a list
}

# A series of measurements taken by a device
<SampledData> CLOSED {
    fhir:Element.id id?;                    # Unique id for inter-element 
                                            # referencing 
    fhir:Element.extension @<Extension>*;   # Additional content defined by 
                                            # implementations 
    fhir:SampledData.origin @<SimpleQuantity>;  # Zero value and units
    fhir:SampledData.period @<decimal>;     # Number of milliseconds between 
                                            # samples 
    fhir:SampledData.factor @<decimal>?;    # Multiply data by this before 
                                            # adding to origin 
    fhir:SampledData.lowerLimit @<decimal>?;  # Lower limit of detection
    fhir:SampledData.upperLimit @<decimal>?;  # Upper limit of detection
    fhir:SampledData.dimensions @<positiveInt>;  # Number of sample points at each 
                                            # time point 
    fhir:SampledData.data @<string>?;       # Decimal values with spaces, or "E" 
                                            # | "U" | "L" 
    fhir:index xsd:integer?                 # Relative position in a list
}

# Primitive Type id
<id> CLOSED {
    fhir:Element.id string?;                # xml:id (or equivalent in JSON)
    fhir:Element.extension @<Extension>*;   # Additional content defined by 
                                            # implementations 
    fhir:value id?;                         # Primitive value for id
    fhir:index xsd:integer?                 # Relative position in a list
}

# Primitive Type positiveInt
<positiveInt> CLOSED {
    fhir:Element.id string?;                # xml:id (or equivalent in JSON)
    fhir:Element.extension @<Extension>*;   # Additional content defined by 
                                            # implementations 
    fhir:value positiveInt?;                # Primitive value for positiveInt
    fhir:index xsd:integer?                 # Relative position in a list
}

# A length - a value with a unit that is a physical distance
<Distance> CLOSED {
    fhir:Element.id id?;                    # Unique id for inter-element 
                                            # referencing 
    fhir:Element.extension @<Extension>*;   # Additional content defined by 
                                            # implementations 
    fhir:Quantity.value @<decimal>?;        # Numerical value (with implicit 
                                            # precision) 
    fhir:Quantity.comparator @<code> AND
    	{fhir:value @fhirvs:quantity-comparator}?;  # < | <= | >= | > - how to 
                                            # understand the value 
    fhir:Quantity.unit @<string>?;          # Unit representation
    fhir:Quantity.system @<uri>?;           # System that defines coded unit form
    fhir:Quantity.code @<code>?;            # Coded form of the unit
    fhir:index xsd:integer?                 # Relative position in a list
}

# Time range defined by start and end date/time
<Period> CLOSED {
    fhir:Element.id id?;                    # Unique id for inter-element 
                                            # referencing 
    fhir:Element.extension @<Extension>*;   # Additional content defined by 
                                            # implementations 
    fhir:Period.start @<dateTime>?;         # Starting time with inclusive 
                                            # boundary 
    fhir:Period.end @<dateTime>?;           # End time with inclusive boundary, 
                                            # if not ongoing 
    fhir:index xsd:integer?                 # Relative position in a list
}

# A length of time
<Duration> CLOSED {
    fhir:Element.id id?;                    # Unique id for inter-element 
                                            # referencing 
    fhir:Element.extension @<Extension>*;   # Additional content defined by 
                                            # implementations 
    fhir:Quantity.value @<decimal>?;        # Numerical value (with implicit 
                                            # precision) 
    fhir:Quantity.comparator @<code> AND
    	{fhir:value @fhirvs:quantity-comparator}?;  # < | <= | >= | > - how to 
                                            # understand the value 
    fhir:Quantity.unit @<string>?;          # Unit representation
    fhir:Quantity.system @<uri>?;           # System that defines coded unit form
    fhir:Quantity.code @<code>?;            # Coded form of the unit
    fhir:index xsd:integer?                 # Relative position in a list
}

# Primitive Type canonical
<canonical> CLOSED {
    fhir:Element.id string?;                # xml:id (or equivalent in JSON)
    fhir:Element.extension @<Extension>*;   # Additional content defined by 
                                            # implementations 
    fhir:value canonical?;                  # Primitive value for canonical
    fhir:index xsd:integer?                 # Relative position in a list
}

# Set of values bounded by low and high
<Range> CLOSED {
    fhir:Element.id id?;                    # Unique id for inter-element 
                                            # referencing 
    fhir:Element.extension @<Extension>*;   # Additional content defined by 
                                            # implementations 
    fhir:Range.low @<SimpleQuantity>?;      # Low limit
    fhir:Range.high @<SimpleQuantity>?;     # High limit
    fhir:index xsd:integer?                 # Relative position in a list
}

# Related artifacts for a knowledge resource
<RelatedArtifact> CLOSED {
    fhir:Element.id id?;                    # Unique id for inter-element 
                                            # referencing 
    fhir:Element.extension @<Extension>*;   # Additional content defined by 
                                            # implementations 
    fhir:RelatedArtifact.type @<code> AND
    	{fhir:value @fhirvs:related-artifact-type};  # documentation | justification | 
                                            # citation | predecessor | successor 
                                            # | derived-from | depends-on | 
                                            # composed-of 
    fhir:RelatedArtifact.label @<string>?;  # Short label
    fhir:RelatedArtifact.display @<string>?;  # Brief description of the related 
                                            # artifact 
    fhir:RelatedArtifact.citation @<markdown>?;  # Bibliographic citation for the 
                                            # artifact 
    fhir:RelatedArtifact.url @<url>?;       # Where the artifact can be accessed
    fhir:RelatedArtifact.document @<Attachment>?;  # What document is being referenced
    fhir:RelatedArtifact.resource @<canonical>?;  # What resource is being referenced
    fhir:index xsd:integer?                 # Relative position in a list
}

# Primitive Type base64Binary
<base64Binary> CLOSED {
    fhir:Element.id string?;                # xml:id (or equivalent in JSON)
    fhir:Element.extension @<Extension>*;   # Additional content defined by 
                                            # implementations 
    fhir:value base64Binary?;               # Primitive value for base64Binary
    fhir:index xsd:integer?                 # Relative position in a list
}

# Describes the context of use for a conformance or knowledge resource
<UsageContext> CLOSED {
    fhir:Element.id id?;                    # Unique id for inter-element 
                                            # referencing 
    fhir:Element.extension @<Extension>*;   # Additional content defined by 
                                            # implementations 
    fhir:UsageContext.code @<Coding>;       # Type of context being specified
    (                                       # Value that defines the context
        fhir:UsageContext.valueCodeableConcept @<CodeableConcept>  |
        fhir:UsageContext.valueQuantity @<Quantity>  |
        fhir:UsageContext.valueRange @<Range>  |
        fhir:UsageContext.valueReference @<Reference> 
    );
    fhir:index xsd:integer?                 # Relative position in a list
}

# A timing schedule that specifies an event that may occur multiple times
<Timing> CLOSED {
    fhir:Element.id id?;                    # Unique id for inter-element 
                                            # referencing 
    fhir:Element.extension @<Extension>*;   # Additional content defined by 
                                            # implementations 
    fhir:BackboneElement.modifierExtension @<Extension>*;  # Extensions that cannot be ignored 
                                            # even if unrecognized 
    fhir:Timing.event @<dateTime>*;         # When the event occurs
    fhir:Timing.repeat @<Timing.repeat>?;   # When the event is to occur
    fhir:Timing.code @<CodeableConcept>?;   # BID | TID | QID | AM | PM | QD | 
                                            # QOD | + 
    fhir:index xsd:integer?                 # Relative position in a list
}

# Definition of a parameter to a module
<ParameterDefinition> CLOSED {
    fhir:Element.id id?;                    # Unique id for inter-element 
                                            # referencing 
    fhir:Element.extension @<Extension>*;   # Additional content defined by 
                                            # implementations 
    fhir:ParameterDefinition.name @<code>?;  # Name used to access the parameter 
                                            # value 
    fhir:ParameterDefinition.use @<code> AND
    	{fhir:value @fhirvs:operation-parameter-use};  # in | out
    fhir:ParameterDefinition.min @<integer>?;  # Minimum cardinality
    fhir:ParameterDefinition.max @<string>?;  # Maximum cardinality (a number of *)
    fhir:ParameterDefinition.documentation @<string>?;  # A brief description of the 
                                            # parameter 
    fhir:ParameterDefinition.type @<code> AND
    	{fhir:value @fhirvs:all-types};  # What type of value
    fhir:ParameterDefinition.profile @<canonical>?;  # What profile the value is expected 
                                            # to be 
    fhir:index xsd:integer?                 # Relative position in a list
}

# Primitive Type dateTime
<dateTime> CLOSED {
    fhir:Element.id string?;                # xml:id (or equivalent in JSON)
    fhir:Element.extension @<Extension>*;   # Additional content defined by 
                                            # implementations 
    fhir:value dateTime?;                   # Primitive value for dateTime
    fhir:index xsd:integer?                 # Relative position in a list
}

# Contributor information
<Contributor> CLOSED {
    fhir:Element.id id?;                    # Unique id for inter-element 
                                            # referencing 
    fhir:Element.extension @<Extension>*;   # Additional content defined by 
                                            # implementations 
    fhir:Contributor.type @<code> AND
    	{fhir:value @fhirvs:contributor-type};  # author | editor | reviewer | 
                                            # endorser 
    fhir:Contributor.name @<string>;        # Who contributed the content
    fhir:Contributor.contact @<ContactDetail>*;  # Contact details of the contributor
    fhir:index xsd:integer?                 # Relative position in a list
}

# Primitive Type oid
<oid> CLOSED {
    fhir:Element.id string?;                # xml:id (or equivalent in JSON)
    fhir:Element.extension @<Extension>*;   # Additional content defined by 
                                            # implementations 
    fhir:value oid?;                        # Primitive value for oid
    fhir:index xsd:integer?                 # Relative position in a list
}

# Primitive Type instant
<instant> CLOSED {
    fhir:Element.id string?;                # xml:id (or equivalent in JSON)
    fhir:Element.extension @<Extension>*;   # Additional content defined by 
                                            # implementations 
    fhir:value instant?;                    # Primitive value for instant
    fhir:index xsd:integer?                 # Relative position in a list
}

# Details of a Technology mediated contact point (phone, fax, email, etc.)
<ContactPoint> CLOSED {
    fhir:Element.id id?;                    # Unique id for inter-element 
                                            # referencing 
    fhir:Element.extension @<Extension>*;   # Additional content defined by 
                                            # implementations 
    fhir:ContactPoint.system @<code> AND
    	{fhir:value @fhirvs:contact-point-system}?;  # phone | fax | email | pager | url 
                                            # | sms | other 
    fhir:ContactPoint.value @<string>?;     # The actual contact point details
    fhir:ContactPoint.use @<code> AND
    	{fhir:value @fhirvs:contact-point-use}?;  # home | work | temp | old | mobile 
                                            # - purpose of this contact point 
    fhir:ContactPoint.rank @<positiveInt>?;  # Specify preferred order of use (1 
                                            # = highest) 
    fhir:ContactPoint.period @<Period>?;    # Time period when the contact point 
                                            # was/is in use 
    fhir:index xsd:integer?                 # Relative position in a list
}

# Name of a human - parts and usage
<HumanName> CLOSED {
    fhir:Element.id id?;                    # Unique id for inter-element 
                                            # referencing 
    fhir:Element.extension @<Extension>*;   # Additional content defined by 
                                            # implementations 
    fhir:HumanName.use @<code> AND
    	{fhir:value @fhirvs:name-use}?;  # usual | official | temp | nickname 
                                            # | anonymous | old | maiden 
    fhir:HumanName.text @<string>?;         # Text representation of the full 
                                            # name 
    fhir:HumanName.family @<string>?;       # Family name (often called 
                                            # 'Surname') 
    fhir:HumanName.given @<string>*;        # Given names (not always 'first'). 
                                            # Includes middle names 
    fhir:HumanName.prefix @<string>*;       # Parts that come before the name
    fhir:HumanName.suffix @<string>*;       # Parts that come after the name
    fhir:HumanName.period @<Period>?;       # Time period when name was/is in use
    fhir:index xsd:integer?                 # Relative position in a list
}

# An amount of economic utility in some recognized currency
<Money> CLOSED {
    fhir:Element.id id?;                    # Unique id for inter-element 
                                            # referencing 
    fhir:Element.extension @<Extension>*;   # Additional content defined by 
                                            # implementations 
    fhir:Money.value @<decimal>?;           # Numerical value (with implicit 
                                            # precision) 
    fhir:Money.currency @<code> AND
    	{fhir:value @fhirvs:currencies}?;  # ISO 4217 Currency Code
    fhir:index xsd:integer?                 # Relative position in a list
}

# Primitive Type markdown
<markdown> CLOSED {
    fhir:Element.id string?;                # xml:id (or equivalent in JSON)
    fhir:Element.extension @<Extension>*;   # Additional content defined by 
                                            # implementations 
    fhir:value markdown?;                   # Primitive value for markdown
    fhir:index xsd:integer?                 # Relative position in a list
}

# A ratio of two Quantity values - a numerator and a denominator
<Ratio> CLOSED {
    fhir:Element.id id?;                    # Unique id for inter-element 
                                            # referencing 
    fhir:Element.extension @<Extension>*;   # Additional content defined by 
                                            # implementations 
    fhir:Ratio.numerator @<Quantity>?;      # Numerator value
    fhir:Ratio.denominator @<Quantity>?;    # Denominator value
    fhir:index xsd:integer?                 # Relative position in a list
}

# A duration of time during which an organism (or a process) has existed
<Age> CLOSED {
    fhir:Element.id id?;                    # Unique id for inter-element 
                                            # referencing 
    fhir:Element.extension @<Extension>*;   # Additional content defined by 
                                            # implementations 
    fhir:Quantity.value @<decimal>?;        # Numerical value (with implicit 
                                            # precision) 
    fhir:Quantity.comparator @<code> AND
    	{fhir:value @fhirvs:quantity-comparator}?;  # < | <= | >= | > - how to 
                                            # understand the value 
    fhir:Quantity.unit @<string>?;          # Unit representation
    fhir:Quantity.system @<uri>?;           # System that defines coded unit form
    fhir:Quantity.code @<code>?;            # Coded form of the unit
    fhir:index xsd:integer?                 # Relative position in a list
}

# Defines an expected trigger for a module
<TriggerDefinition> CLOSED {
    fhir:Element.id id?;                    # Unique id for inter-element 
                                            # referencing 
    fhir:Element.extension @<Extension>*;   # Additional content defined by 
                                            # implementations 
    fhir:TriggerDefinition.type @<code> AND
    	{fhir:value @fhirvs:trigger-type};  # named-event | periodic | 
                                            # data-changed | data-added | 
                                            # data-modified | data-removed | 
                                            # data-accessed | data-access-ended 
    fhir:TriggerDefinition.name @<string>?;  # Name or URI that identifies the 
                                            # event 
    (                                       # Timing of the event
        fhir:TriggerDefinition.timingTiming @<Timing>  |
        fhir:TriggerDefinition.timingReference @<Reference>  |
        fhir:TriggerDefinition.timingDate @<date>  |
        fhir:TriggerDefinition.timingDateTime @<dateTime> 
    )?;
    fhir:TriggerDefinition.data @<DataRequirement>*;  # Triggering data of the event 
                                            # (multiple = 'and') 
    fhir:TriggerDefinition.condition @<Expression>?;  # Whether the event triggers 
                                            # (boolean expression) 
    fhir:index xsd:integer?                 # Relative position in a list
}

# Primitive Type url
<url> CLOSED {
    fhir:Element.id string?;                # xml:id (or equivalent in JSON)
    fhir:Element.extension @<Extension>*;   # Additional content defined by 
                                            # implementations 
    fhir:value url?;                        # Primitive value for url
    fhir:index xsd:integer?                 # Relative position in a list
}

# Text node with attribution
<Annotation> CLOSED {
    fhir:Element.id id?;                    # Unique id for inter-element 
                                            # referencing 
    fhir:Element.extension @<Extension>*;   # Additional content defined by 
                                            # implementations 
    (                                       # Individual responsible for the 
                                            # annotation 
        fhir:Annotation.authorReference @<Reference>  |
        fhir:Annotation.authorString @<string> 
    )?;
    fhir:Annotation.time @<dateTime>?;      # When the annotation was made
    fhir:Annotation.text @<markdown>;       # The annotation  - text content (as 
                                            # markdown) 
    fhir:index xsd:integer?                 # Relative position in a list
}

# Contact information
<ContactDetail> CLOSED {
    fhir:Element.id id?;                    # Unique id for inter-element 
                                            # referencing 
    fhir:Element.extension @<Extension>*;   # Additional content defined by 
                                            # implementations 
    fhir:ContactDetail.name @<string>?;     # Name of an individual to contact
    fhir:ContactDetail.telecom @<ContactPoint>*;  # Contact details for individual or 
                                            # organization 
    fhir:index xsd:integer?                 # Relative position in a list
}

# An expression that can be used to generate a value
<Expression> CLOSED {
    fhir:Element.id id?;                    # Unique id for inter-element 
                                            # referencing 
    fhir:Element.extension @<Extension>*;   # Additional content defined by 
                                            # implementations 
    fhir:Expression.description @<string>?;  # Natural language description of 
                                            # the condition 
    fhir:Expression.name @<id>?;            # Short name assigned to expression 
                                            # for reuse 
    fhir:Expression.language @<code>;       # text/cql | text/fhirpath | 
                                            # application/x-fhir-query | 
                                            # text/cql-identifier | 
                                            # text/cql-expression | etc. 
    fhir:Expression.expression @<string>?;  # Expression in specified language
    fhir:Expression.reference @<uri>?;      # Where the expression is found
    fhir:index xsd:integer?                 # Relative position in a list
}

# Reference to a resource or a concept
<CodeableReference> CLOSED {
    fhir:Element.id id?;                    # Unique id for inter-element 
                                            # referencing 
    fhir:Element.extension @<Extension>*;   # Additional content defined by 
                                            # implementations 
    fhir:CodeableReference.concept @<CodeableConcept>?;  # Reference to a concept (by class)
    fhir:CodeableReference.reference @<Reference>?;  # Reference to a resource (by 
                                            # instance) 
    fhir:index xsd:integer?                 # Relative position in a list
}

# A Signature - XML DigSig, JWS, Graphical image of signature, etc.
<Signature> CLOSED {
    fhir:Element.id id?;                    # Unique id for inter-element 
                                            # referencing 
    fhir:Element.extension @<Extension>*;   # Additional content defined by 
                                            # implementations 
    fhir:Signature.type @<Coding>+;         # Indication of the reason the 
                                            # entity signed the object(s) 
    fhir:Signature.when @<instant>;         # When the signature was created
    fhir:Signature.who @<Reference>;        # Who signed
    fhir:Signature.onBehalfOf @<Reference>?;  # The party represented
    fhir:Signature.targetFormat @<code> AND
    	{fhir:value @fhirvs:mimetypes}?;  # The technical format of the signed 
                                            # resources 
    fhir:Signature.sigFormat @<code> AND
    	{fhir:value @fhirvs:mimetypes}?;  # The technical format of the 
                                            # signature 
    fhir:Signature.data @<base64Binary>?;   # The actual signature content (XML 
                                            # DigSig. JWS, picture, etc.) 
    fhir:index xsd:integer?                 # Relative position in a list
}

# Primitive Type unsignedInt
<unsignedInt> CLOSED {
    fhir:Element.id string?;                # xml:id (or equivalent in JSON)
    fhir:Element.extension @<Extension>*;   # Additional content defined by 
                                            # implementations 
    fhir:value unsignedInt?;                # Primitive value for unsignedInt
    fhir:index xsd:integer?                 # Relative position in a list
}

# Primitive Type time
<time> CLOSED {
    fhir:Element.id string?;                # xml:id (or equivalent in JSON)
    fhir:Element.extension @<Extension>*;   # Additional content defined by 
                                            # implementations 
    fhir:value time?;                       # Primitive value for time
    fhir:index xsd:integer?                 # Relative position in a list
}

# A fixed quantity (no comparator)
<SimpleQuantity> CLOSED {
    fhir:Element.id id?;                    # Unique id for inter-element 
                                            # referencing 
    fhir:Element.extension @<Extension>*;   # Additional content defined by 
                                            # implementations 
    fhir:Quantity.value @<decimal>?;        # Numerical value (with implicit 
                                            # precision) 
    fhir:Quantity.unit @<string>?;          # Unit representation
    fhir:Quantity.system @<uri>?;           # System that defines coded unit form
    fhir:Quantity.code @<code>?;            # Coded form of the unit
    fhir:index xsd:integer?                 # Relative position in a list
}

# Amount of medication administered
<Dosage.doseAndRate> CLOSED {
    fhir:Element.id string?;                # Unique id for inter-element 
                                            # referencing 
    fhir:Element.extension @<Extension>*;   # Additional content defined by 
                                            # implementations 
    fhir:Dosage.doseAndRate.type @<CodeableConcept>?;  # The kind of dose or rate specified
    (                                       # Amount of medication per dose
        fhir:Dosage.doseAndRate.doseRange @<Range>  |
        fhir:Dosage.doseAndRate.doseQuantity @<SimpleQuantity> 
    )?;
    (                                       # Amount of medication per unit of 
                                            # time 
        fhir:Dosage.doseAndRate.rateRatio @<Ratio>  |
        fhir:Dosage.doseAndRate.rateRange @<Range>  |
        fhir:Dosage.doseAndRate.rateQuantity @<SimpleQuantity> 
    )?;
    fhir:index xsd:integer?                 # Relative position in a list
}

# When the event is to occur
<Timing.repeat> CLOSED {
    fhir:Element.id string?;                # Unique id for inter-element 
                                            # referencing 
    fhir:Element.extension @<Extension>*;   # Additional content defined by 
                                            # implementations 
    (                                       # Length/Range of lengths, or (Start 
                                            # and/or end) limits 
        fhir:Timing.repeat.boundsDuration @<Duration>  |
        fhir:Timing.repeat.boundsRange @<Range>  |
        fhir:Timing.repeat.boundsPeriod @<Period> 
    )?;
    fhir:Timing.repeat.count @<positiveInt>?;  # Number of times to repeat
    fhir:Timing.repeat.countMax @<positiveInt>?;  # Maximum number of times to repeat
    fhir:Timing.repeat.duration @<decimal>?;  # How long when it happens
    fhir:Timing.repeat.durationMax @<decimal>?;  # How long when it happens (Max)
    fhir:Timing.repeat.durationUnit @<code> AND
    	{fhir:value @fhirvs:units-of-time}?;  # s | min | h | d | wk | mo | a - 
                                            # unit of time (UCUM) 
    fhir:Timing.repeat.frequency @<positiveInt>?;  # Event occurs frequency times per 
                                            # period 
    fhir:Timing.repeat.frequencyMax @<positiveInt>?;  # Event occurs up to frequencyMax 
                                            # times per period 
    fhir:Timing.repeat.period @<decimal>?;  # Event occurs frequency times per 
                                            # period 
    fhir:Timing.repeat.periodMax @<decimal>?;  # Upper limit of period (3-4 hours)
    fhir:Timing.repeat.periodUnit @<code> AND
    	{fhir:value @fhirvs:units-of-time}?;  # s | min | h | d | wk | mo | a - 
                                            # unit of time (UCUM) 
    fhir:Timing.repeat.dayOfWeek @<code> AND
    	{fhir:value @fhirvs:days-of-week}*;  # mon | tue | wed | thu | fri | sat 
                                            # | sun 
    fhir:Timing.repeat.timeOfDay @<time>*;  # Time of day for action
    fhir:Timing.repeat.when @<code> AND
    	{fhir:value @fhirvs:event-timing}*;  # Code for time period of occurrence
    fhir:Timing.repeat.offset @<unsignedInt>?;  # Minutes from event (before or 
                                            # after) 
    fhir:index xsd:integer?                 # Relative position in a list
}

# What dates/date ranges are expected
<DataRequirement.dateFilter> CLOSED {
    fhir:Element.id string?;                # Unique id for inter-element 
                                            # referencing 
    fhir:Element.extension @<Extension>*;   # Additional content defined by 
                                            # implementations 
    fhir:DataRequirement.dateFilter.path @<string>?;  # A date-valued attribute to filter 
                                            # on 
    fhir:DataRequirement.dateFilter.searchParam @<string>?;  # A date valued parameter to search 
                                            # on 
    (                                       # The value of the filter, as a 
                                            # Period, DateTime, or Duration 
                                            # value 
        fhir:DataRequirement.dateFilter.valueDateTime @<dateTime>  |
        fhir:DataRequirement.dateFilter.valuePeriod @<Period>  |
        fhir:DataRequirement.dateFilter.valueDuration @<Duration> 
    )?;
    fhir:index xsd:integer?                 # Relative position in a list
}

# Order of the results
<DataRequirement.sort> CLOSED {
    fhir:Element.id string?;                # Unique id for inter-element 
                                            # referencing 
    fhir:Element.extension @<Extension>*;   # Additional content defined by 
                                            # implementations 
    fhir:DataRequirement.sort.path @<string>;  # The name of the attribute to 
                                            # perform the sort 
    fhir:DataRequirement.sort.direction @<code> AND
    	{fhir:value @fhirvs:sort-direction};  # ascending | descending
    fhir:index xsd:integer?                 # Relative position in a list
}

# What codes are expected
<DataRequirement.codeFilter> CLOSED {
    fhir:Element.id string?;                # Unique id for inter-element 
                                            # referencing 
    fhir:Element.extension @<Extension>*;   # Additional content defined by 
                                            # implementations 
    fhir:DataRequirement.codeFilter.path @<string>?;  # A code-valued attribute to filter 
                                            # on 
    fhir:DataRequirement.codeFilter.searchParam @<string>?;  # A coded (token) parameter to 
                                            # search on 
    fhir:DataRequirement.codeFilter.valueSet @<canonical>?;  # Valueset for the filter
    fhir:DataRequirement.codeFilter.code @<Coding>*;  # What code is expected
    fhir:index xsd:integer?                 # Relative position in a list
}

#---------------------- Reference Types -------------------

#---------------------- Value Sets ------------------------

# A unit of time (units from UCUM).
fhirvs:units-of-time ["s" "min" "h" "d" "wk" "mo" "a"]

# The type of an address (physical / postal).
fhirvs:address-type ["postal" "physical" "both"]

# The type of trigger.
fhirvs:trigger-type ["named-event" "periodic" "data-changed" "data-added" "data-modified" "data-removed" "data-accessed" "data-access-ended"]

# The type of contributor.
fhirvs:contributor-type ["author" "editor" "reviewer" "endorser"]

# Telecommunications form for contact point.
fhirvs:contact-point-system ["phone" "fax" "email" "pager" "url" "sms" "other"]

# The status of a resource narrative.
fhirvs:narrative-status ["generated" "extensions" "additional" "empty"]

# The use of a human name.
fhirvs:name-use ["usual" "official" "temp" "nickname" "anonymous" "old" "maiden"]

# Identifies the purpose for this identifier, if known .
fhirvs:identifier-use ["usual" "official" "temp" "secondary" "old"]

# Type for quality report.
fhirvs:quality-type ["indel" "snp" "unknown"]

# Type for orientation.
fhirvs:orientation-type ["sense" "antisense"]

# Type if a sequence -- DNA, RNA, or amino acid sequence.
fhirvs:sequence-type ["aa" "dna" "rna"]

# Whether an operation parameter is an input or an output parameter.
fhirvs:operation-parameter-use ["in" "out"]

# The use of an address.
fhirvs:address-use ["home" "work" "temp" "old" "billing"]

# Real world event relating to the schedule.
fhirvs:event-timing ["MORN" "MORN.early" "MORN.late" "NOON" "AFT" "AFT.early" "AFT.late" "EVE" "EVE.early" "EVE.late" "NIGHT" "PHS" "HS" "WAKE" "C" "CM" "CD" "CV" "AC" "ACM" "ACD" "ACV" "PC" "PCM" "PCD" "PCV"]

# The days of the week.
fhirvs:days-of-week ["mon" "tue" "wed" "thu" "fri" "sat" "sun"]

# The type of relationship to the related artifact.
fhirvs:related-artifact-type ["documentation" "justification" "citation" "predecessor" "successor" "derived-from" "depends-on" "composed-of"]

# How the Quantity should be understood and represented.
fhirvs:quantity-comparator ["<" "<=" ">=" ">"]

# A list of all the concrete types defined in this version of the FHIR specification - Abstract Types, Data Types and Resource Types.
fhirvs:all-types ["Address" "Age" "Annotation" "Attachment" "BackboneElement" "CodeableConcept" "CodeableReference" "Coding" "ContactDetail" "ContactPoint" "Contributor" "Count" "DataRequirement" "Distance" "Dosage" "Duration" "Element" "ElementDefinition" "Expression" "Extension" "HumanName" "Identifier" "MarketingStatus" "Meta" "Money" "MoneyQuantity" "Narrative" "ParameterDefinition" "Period" "Population" "ProdCharacteristic" "ProductShelfLife" "Quantity" "Range" "Ratio" "RatioRange" "Reference" "RelatedArtifact" "SampledData" "Signature" "SimpleQuantity" "Timing" "TriggerDefinition" "UsageContext" "base64Binary" "boolean" "canonical" "code" "date" "dateTime" "decimal" "id" "instant" "integer" "markdown" "oid" "positiveInt" "string" "time" "unsignedInt" "uri" "url" "uuid" "xhtml" "Resource" "Binary" "Bundle" "DomainResource" "Account" "ActivityDefinition" "AdministrableProductDefinition" "AdverseEvent" "AllergyIntolerance" "Appointment" "AppointmentResponse" "AuditEvent" "Basic" "BiologicallyDerivedProduct" "BodyStructure" "CapabilityStatement" "CarePlan" "CareTeam" "CatalogEntry" "ChargeItem" "ChargeItemDefinition" "Citation" "Claim" "ClaimResponse" "ClinicalImpression" "ClinicalUseDefinition" "CodeSystem" "Communication" "CommunicationRequest" "CompartmentDefinition" "Composition" "ConceptMap" "Condition" "Consent" "Contract" "Coverage" "CoverageEligibilityRequest" "CoverageEligibilityResponse" "DetectedIssue" "Device" "DeviceDefinition" "DeviceMetric" "DeviceRequest" "DeviceUseStatement" "DiagnosticReport" "DocumentManifest" "DocumentReference" "Encounter" "Endpoint" "EnrollmentRequest" "EnrollmentResponse" "EpisodeOfCare" "EventDefinition" "Evidence" "EvidenceReport" "EvidenceVariable" "ExampleScenario" "ExplanationOfBenefit" "FamilyMemberHistory" "Flag" "Goal" "GraphDefinition" "Group" "GuidanceResponse" "HealthcareService" "ImagingStudy" "Immunization" "ImmunizationEvaluation" "ImmunizationRecommendation" "ImplementationGuide" "Ingredient" "InsurancePlan" "Invoice" "Library" "Linkage" "List" "Location" "ManufacturedItemDefinition" "Measure" "MeasureReport" "Media" "Medication" "MedicationAdministration" "MedicationDispense" "MedicationKnowledge" "MedicationRequest" "MedicationStatement" "MedicinalProductDefinition" "MessageDefinition" "MessageHeader" "MolecularSequence" "NamingSystem" "NutritionOrder" "NutritionProduct" "Observation" "ObservationDefinition" "OperationDefinition" "OperationOutcome" "Organization" "OrganizationAffiliation" "PackagedProductDefinition" "Patient" "PaymentNotice" "PaymentReconciliation" "Person" "PlanDefinition" "Practitioner" "PractitionerRole" "Procedure" "Provenance" "Questionnaire" "QuestionnaireResponse" "RegulatedAuthorization" "RelatedPerson" "RequestGroup" "ResearchDefinition" "ResearchElementDefinition" "ResearchStudy" "ResearchSubject" "RiskAssessment" "Schedule" "SearchParameter" "ServiceRequest" "Slot" "Specimen" "SpecimenDefinition" "StructureDefinition" "StructureMap" "Subscription" "SubscriptionStatus" "SubscriptionTopic" "Substance" "SubstanceDefinition" "SupplyDelivery" "SupplyRequest" "Task" "TerminologyCapabilities" "TestReport" "TestScript" "ValueSet" "VerificationResult" "VisionPrescription" "Parameters" "Type" "Any"]

# Use of contact point.
fhirvs:contact-point-use ["home" "work" "temp" "old" "mobile"]

# Type for strand.
fhirvs:strand-type ["watson" "crick"]

# Currency codes from ISO 4217 (see https://www.iso.org/iso-4217-currency-codes.html)
fhirvs:currencies ["AED" "AFN" "ALL" "AMD" "ANG" "AOA" "ARS" "AUD" "AWG" "AZN" "BAM" "BBD" "BDT" "BGN" "BHD" "BIF" "BMD" "BND" "BOB" "BOV" "BRL" "BSD" "BTN" "BWP" "BYN" "BZD" "CAD" "CDF" "CHE" "CHF" "CHW" "CLF" "CLP" "CNY" "COP" "COU" "CRC" "CUC" "CUP" "CVE" "CZK" "DJF" "DKK" "DOP" "DZD" "EGP" "ERN" "ETB" "EUR" "FJD" "FKP" "GBP" "GEL" "GGP" "GHS" "GIP" "GMD" "GNF" "GTQ" "GYD" "HKD" "HNL" "HRK" "HTG" "HUF" "IDR" "ILS" "IMP" "INR" "IQD" "IRR" "ISK" "JEP" "JMD" "JOD" "JPY" "KES" "KGS" "KHR" "KMF" "KPW" "KRW" "KWD" "KYD" "KZT" "LAK" "LBP" "LKR" "LRD" "LSL" "LYD" "MAD" "MDL" "MGA" "MKD" "MMK" "MNT" "MOP" "MRU" "MUR" "MVR" "MWK" "MXN" "MXV" "MYR" "MZN" "NAD" "NGN" "NIO" "NOK" "NPR" "NZD" "OMR" "PAB" "PEN" "PGK" "PHP" "PKR" "PLN" "PYG" "QAR" "RON" "RSD" "RUB" "RWF" "SAR" "SBD" "SCR" "SDG" "SEK" "SGD" "SHP" "SLL" "SOS" "SRD" "SSP" "STN" "SVC" "SYP" "SZL" "THB" "TJS" "TMT" "TND" "TOP" "TRY" "TTD" "TVD" "TWD" "TZS" "UAH" "UGX" "USD" "USN" "UYI" "UYU" "UZS" "VEF" "VND" "VUV" "WST" "XAF" "XAG" "XAU" "XBA" "XBB" "XBC" "XBD" "XCD" "XDR" "XOF" "XPD" "XPF" "XPT" "XSU" "XTS" "XUA" "XXX" "YER" "ZAR" "ZMW" "ZWL"]

# The possible sort directions, ascending or descending.
fhirvs:sort-direction ["ascending" "descending"]

# This value set includes all possible codes from BCP-13 (http://tools.ietf.org/html/bcp13)
fhirvs:mimetypes EXTERNAL

# Type for access of external URI.
fhirvs:repository-type ["directlink" "openapi" "login" "oauth" "other"]