@prefix fhir: <http://hl7.org/fhir/> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix sct: <http://snomed.info/id/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

# - resource -------------------------------------------------------------------

<http://hl7.org/fhir/MedicationDispense/meddisp0306> a fhir:MedicationDispense;
  fhir:nodeRole fhir:treeRoot;
  fhir:Resource.id [ fhir:value "meddisp0306"];
  fhir:DomainResource.text [
     fhir:Narrative.status [ fhir:value "generated" ];
     fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative</b></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource &quot;meddisp0306&quot; </p></div><p><b>status</b>: in-progress</p><p><b>medication</b>: <a name=\"med0303\"> </a></p><blockquote><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource &quot;med0303&quot; </p></div><p><b>code</b>: Alemtuzumab 10mg/ml (Lemtrada) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/3.1.0/CodeSystem-v3-rxNorm.html\">RxNorm</a>#1594660)</span></p></blockquote><p><b>subject</b>: <a href=\"patient-pat1.html\">Patient/pat1: Donald Duck</a> &quot;Duck DONALD&quot;</p><h3>Performers</h3><table class=\"grid\"><tr><td>-</td><td><b>Actor</b></td></tr><tr><td>*</td><td><a href=\"practitioner-f006.html\">Practitioner/f006</a> &quot;Rob VAN DEN BERK&quot;</td></tr></table><p><b>authorizingPrescription</b>: <a href=\"medicationrequest-medrx0317.html\">MedicationRequest/medrx0317</a></p><p><b>type</b>: Daily Fill <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/3.1.0/CodeSystem-v3-ActCode.html\">ActCode</a>#DF)</span></p><p><b>quantity</b>: 5(unit 415818006 from http://snomed.info/sct)<span style=\"background: LightGoldenRodYellow\"> (Details: SNOMED CT code 415818006 = 'Vial')</span></p><p><b>daysSupply</b>: 7 Day<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code d = 'd')</span></p><p><b>whenPrepared</b>: 2015-01-15T10:20:00Z</p></div>"
  ];
  fhir:DomainResource.contained [
     a fhir:Medication;
     fhir:index 0;
     fhir:Resource.id [ fhir:value "med0303" ];
     fhir:Medication.code [
       fhir:CodeableConcept.coding [
         fhir:index 0;
         fhir:Coding.system [ fhir:value "http://www.nlm.nih.gov/research/umls/rxnorm" ];
         fhir:Coding.code [ fhir:value "1594660" ];
         fhir:Coding.display [ fhir:value "Alemtuzumab 10mg/ml (Lemtrada)" ]
       ]
     ]
  ];
  fhir:MedicationDispense.status [ fhir:value "in-progress"];
  fhir:MedicationDispense.medicationReference [
     fhir:Reference.reference [ fhir:value "#med0303" ];
     fhir:Reference.display [ fhir:value "Alemtuzumab 10mg/ml (Lemtrada)" ]
  ];
  fhir:MedicationDispense.subject [
     fhir:link <http://hl7.org/fhir/Patient/pat1>;
     fhir:Reference.reference [ fhir:value "Patient/pat1" ];
     fhir:Reference.display [ fhir:value "Donald Duck" ]
  ];
  fhir:MedicationDispense.performer [
     fhir:index 0;
     fhir:MedicationDispense.performer.actor [
       fhir:link <http://hl7.org/fhir/Practitioner/f006>;
       fhir:Reference.reference [ fhir:value "Practitioner/f006" ]
     ]
  ];
  fhir:MedicationDispense.authorizingPrescription [
     fhir:index 0;
     fhir:link <http://hl7.org/fhir/MedicationRequest/medrx0317>;
     fhir:Reference.reference [ fhir:value "MedicationRequest/medrx0317" ]
  ];
  fhir:MedicationDispense.type [
     fhir:CodeableConcept.coding [
       fhir:index 0;
       fhir:Coding.system [ fhir:value "http://terminology.hl7.org/CodeSystem/v3-ActCode" ];
       fhir:Coding.code [ fhir:value "DF" ];
       fhir:Coding.display [ fhir:value "Daily Fill" ]
     ]
  ];
  fhir:MedicationDispense.quantity [
     fhir:Quantity.value [ fhir:value "5"^^xsd:decimal ];
     fhir:Quantity.system [ fhir:value "http://snomed.info/sct" ];
     fhir:Quantity.code [ fhir:value "415818006" ]
  ];
  fhir:MedicationDispense.daysSupply [
     fhir:Quantity.value [ fhir:value "7"^^xsd:decimal ];
     fhir:Quantity.unit [ fhir:value "Day" ];
     fhir:Quantity.system [ fhir:value "http://unitsofmeasure.org" ];
     fhir:Quantity.code [ fhir:value "d" ]
  ];
  fhir:MedicationDispense.whenPrepared [ fhir:value "2015-01-15T10:20:00Z"^^xsd:dateTime];
  fhir:MedicationDispense.dosageInstruction [
     fhir:index 0;
     fhir:Dosage.sequence [ fhir:value "1"^^xsd:integer ];
     fhir:Dosage.text [ fhir:value "Rapid daily-dose escalation, until tolerated, from 3 mg/d, and then 10 mg/d, to the recommended maintenance dose of 30 mg IV over 120 min, 3 times per wk on alternate days for up to 12 wk" ];
     fhir:Dosage.additionalInstruction [
       fhir:index 0;
       fhir:CodeableConcept.text [ fhir:value "Rapidly increase dose until tolerated" ]
     ], [
       fhir:index 1;
       fhir:CodeableConcept.text [ fhir:value "Administer on alternate days" ]
     ];
     fhir:Dosage.timing [
       fhir:Timing.repeat [
         fhir:Timing.repeat.duration [ fhir:value "12"^^xsd:decimal ];
         fhir:Timing.repeat.durationUnit [ fhir:value "wk" ];
         fhir:Timing.repeat.frequency [ fhir:value "3"^^xsd:positiveInteger ];
         fhir:Timing.repeat.period [ fhir:value "1"^^xsd:decimal ];
         fhir:Timing.repeat.periodUnit [ fhir:value "wk" ]
       ]
     ];
     fhir:Dosage.route [
       fhir:CodeableConcept.coding [
         fhir:index 0;
         a sct:47625008;
         fhir:Coding.system [ fhir:value "http://snomed.info/sct" ];
         fhir:Coding.code [ fhir:value "47625008" ];
         fhir:Coding.display [ fhir:value "Intravenous route (qualifier value)" ]
       ]
     ];
     fhir:Dosage.method [
       fhir:CodeableConcept.coding [
         fhir:index 0;
         a sct:422145002;
         fhir:Coding.system [ fhir:value "http://snomed.info/sct" ];
         fhir:Coding.code [ fhir:value "422145002" ];
         fhir:Coding.display [ fhir:value "Inject - dosing instruction imperative (qualifier value)" ]
       ]
     ];
     fhir:Dosage.doseAndRate [
       fhir:index 0;
       fhir:Dosage.doseAndRate.type [
         fhir:CodeableConcept.coding [
           fhir:index 0;
           fhir:Coding.system [ fhir:value "http://terminology.hl7.org/CodeSystem/dose-rate-type" ];
           fhir:Coding.code [ fhir:value "calculated" ];
           fhir:Coding.display [ fhir:value "Calculated" ]
         ]
       ];
       fhir:Dosage.doseAndRate.doseQuantity [
         fhir:Quantity.value [ fhir:value "3"^^xsd:decimal ];
         fhir:Quantity.unit [ fhir:value "mg" ];
         fhir:Quantity.system [ fhir:value "http://unitsofmeasure.org" ];
         fhir:Quantity.code [ fhir:value "mg" ]
       ]
     ]
  ], [
     fhir:index 1;
     fhir:Dosage.sequence [ fhir:value "2"^^xsd:integer ];
     fhir:Dosage.text [ fhir:value "Rapid daily-dose escalation, until tolerated, from 3 mg/d, and then 10 mg/d, to the recommended maintenance dose of 30 mg IV over 120 min, 3 times per wk on alternate days for up to 12 wk" ];
     fhir:Dosage.additionalInstruction [
       fhir:index 0;
       fhir:CodeableConcept.text [ fhir:value "Rapidly increase dose until tolerated" ]
     ], [
       fhir:index 1;
       fhir:CodeableConcept.text [ fhir:value "Administer on alternate days" ]
     ];
     fhir:Dosage.timing [
       fhir:Timing.repeat [
         fhir:Timing.repeat.duration [ fhir:value "12"^^xsd:decimal ];
         fhir:Timing.repeat.durationUnit [ fhir:value "wk" ];
         fhir:Timing.repeat.frequency [ fhir:value "3"^^xsd:positiveInteger ];
         fhir:Timing.repeat.period [ fhir:value "1"^^xsd:decimal ];
         fhir:Timing.repeat.periodUnit [ fhir:value "wk" ]
       ]
     ];
     fhir:Dosage.route [
       fhir:CodeableConcept.coding [
         fhir:index 0;
         a sct:47625008;
         fhir:Coding.system [ fhir:value "http://snomed.info/sct" ];
         fhir:Coding.code [ fhir:value "47625008" ];
         fhir:Coding.display [ fhir:value "Intravenous route (qualifier value)" ]
       ]
     ];
     fhir:Dosage.method [
       fhir:CodeableConcept.coding [
         fhir:index 0;
         a sct:422145002;
         fhir:Coding.system [ fhir:value "http://snomed.info/sct" ];
         fhir:Coding.code [ fhir:value "422145002" ];
         fhir:Coding.display [ fhir:value "Inject - dosing instruction imperative (qualifier value)" ]
       ]
     ];
     fhir:Dosage.doseAndRate [
       fhir:index 0;
       fhir:Dosage.doseAndRate.type [
         fhir:CodeableConcept.coding [
           fhir:index 0;
           fhir:Coding.system [ fhir:value "http://terminology.hl7.org/CodeSystem/dose-rate-type" ];
           fhir:Coding.code [ fhir:value "calculated" ];
           fhir:Coding.display [ fhir:value "Calculated" ]
         ]
       ];
       fhir:Dosage.doseAndRate.doseQuantity [
         fhir:Quantity.value [ fhir:value "10"^^xsd:decimal ];
         fhir:Quantity.unit [ fhir:value "mg" ];
         fhir:Quantity.system [ fhir:value "http://unitsofmeasure.org" ];
         fhir:Quantity.code [ fhir:value "mg" ]
       ]
     ]
  ], [
     fhir:index 2;
     fhir:Dosage.sequence [ fhir:value "3"^^xsd:integer ];
     fhir:Dosage.text [ fhir:value "Rapid daily-dose escalation, until tolerated, from 3 mg/d, and then 10 mg/d, to the recommended maintenance dose of 30 mg IV over 120 min, 3 times per wk on alternate days for up to 12 wk" ];
     fhir:Dosage.additionalInstruction [
       fhir:index 0;
       fhir:CodeableConcept.text [ fhir:value "Rapidly increase dose until tolerated" ]
     ], [
       fhir:index 1;
       fhir:CodeableConcept.text [ fhir:value "Administer on alternate days" ]
     ];
     fhir:Dosage.timing [
       fhir:Timing.repeat [
         fhir:Timing.repeat.duration [ fhir:value "12"^^xsd:decimal ];
         fhir:Timing.repeat.durationUnit [ fhir:value "wk" ];
         fhir:Timing.repeat.frequency [ fhir:value "3"^^xsd:positiveInteger ];
         fhir:Timing.repeat.period [ fhir:value "1"^^xsd:decimal ];
         fhir:Timing.repeat.periodUnit [ fhir:value "wk" ]
       ]
     ];
     fhir:Dosage.route [
       fhir:CodeableConcept.coding [
         fhir:index 0;
         a sct:47625008;
         fhir:Coding.system [ fhir:value "http://snomed.info/sct" ];
         fhir:Coding.code [ fhir:value "47625008" ];
         fhir:Coding.display [ fhir:value "Intravenous route (qualifier value)" ]
       ]
     ];
     fhir:Dosage.method [
       fhir:CodeableConcept.coding [
         fhir:index 0;
         a sct:422145002;
         fhir:Coding.system [ fhir:value "http://snomed.info/sct" ];
         fhir:Coding.code [ fhir:value "422145002" ];
         fhir:Coding.display [ fhir:value "Inject - dosing instruction imperative (qualifier value)" ]
       ]
     ];
     fhir:Dosage.doseAndRate [
       fhir:index 0;
       fhir:Dosage.doseAndRate.type [
         fhir:CodeableConcept.coding [
           fhir:index 0;
           fhir:Coding.system [ fhir:value "http://terminology.hl7.org/CodeSystem/dose-rate-type" ];
           fhir:Coding.code [ fhir:value "calculated" ];
           fhir:Coding.display [ fhir:value "Calculated" ]
         ]
       ];
       fhir:Dosage.doseAndRate.doseQuantity [
         fhir:Quantity.value [ fhir:value "30"^^xsd:decimal ];
         fhir:Quantity.unit [ fhir:value "mg" ];
         fhir:Quantity.system [ fhir:value "http://unitsofmeasure.org" ];
         fhir:Quantity.code [ fhir:value "mg" ]
       ]
     ]
  ] .

<http://hl7.org/fhir/Patient/pat1> a fhir:Patient .

<http://hl7.org/fhir/Practitioner/f006> a fhir:Practitioner .

<http://hl7.org/fhir/MedicationRequest/medrx0317> a fhir:MedicationRequest .

# - ontology header ------------------------------------------------------------

<http://hl7.org/fhir/MedicationDispense/meddisp0306.ttl> a owl:Ontology;
  owl:imports fhir:fhir.ttl;
  owl:versionIRI <http://build.fhir.org/MedicationDispense/meddisp0306.ttl> .

# -------------------------------------------------------------------------------------