@prefix fhir: <http://hl7.org/fhir/> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

# - resource -------------------------------------------------------------------

<http://hl7.org/fhir/EvidenceVariable/example-Stroke-Thrombolysis-Trialists-2014-2016-IPD-MA-Cohort> a fhir:EvidenceVariable;
  fhir:nodeRole fhir:treeRoot;
  fhir:Resource.id [ fhir:value "example-Stroke-Thrombolysis-Trialists-2014-2016-IPD-MA-Cohort"];
  fhir:DomainResource.text [
     fhir:Narrative.status [ fhir:value "generated" ];
     fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\">\n      <p>\n        Stroke Thrombolysis Trialists’ Collaborators Group collection used for individual patient data meta-analysis\n      </p>\n	</div>"
  ];
  fhir:EvidenceVariable.name [ fhir:value "Stroke Thrombolysis Trialists’ 2014-2016 IPD-MA Cohort"];
  fhir:EvidenceVariable.title [ fhir:value "Stroke Thrombolysis Trialists’ Collaborators Group collection used for individual patient data meta-analysis"];
  fhir:EvidenceVariable.status [ fhir:value "draft"];
  fhir:EvidenceVariable.useContext [
     fhir:index 0;
     fhir:UsageContext.code [
       fhir:Coding.system [ fhir:value "http://terminology.hl7.org/CodeSystem/usage-context-type" ];
       fhir:Coding.code [ fhir:value "focus" ]
     ];
     fhir:UsageContext.valueCodeableConcept [
       fhir:CodeableConcept.text [ fhir:value "Stroke" ]
     ]
  ];
  fhir:EvidenceVariable.relatedArtifact [
     fhir:index 0;
     fhir:RelatedArtifact.type [ fhir:value "citation" ];
     fhir:RelatedArtifact.label [ fhir:value "Emberson 2014" ];
     fhir:RelatedArtifact.display [ fhir:value "Effect of treatment delay, age, and stroke severity on the effects of intravenous thrombolysis with alteplase for acute ischaemic stroke: a meta-analysis of individual patient data from randomised trials." ];
     fhir:RelatedArtifact.citation [ fhir:value "Emberson J, Lees KR, Lyden P, Blackwell L, Albers G, Bluhmki E, et al;Stroke Thrombolysis Trialists' Collaborative Group. Effect of treatment delay, age, and stroke severity on the effects of intravenous thrombolysis with alteplase for acute ischaemic stroke: a meta-analysis of individual patient data from randomised trials. Lancet 2014 Nov 29;384(9958):1929-35 PMID 25106063" ];
     fhir:RelatedArtifact.url [ fhir:value "https://doi.org/10.1016/S0140-6736(14)60584-5" ]
  ], [
     fhir:index 1;
     fhir:RelatedArtifact.type [ fhir:value "citation" ];
     fhir:RelatedArtifact.label [ fhir:value "Lees 2016" ];
     fhir:RelatedArtifact.display [ fhir:value "Figure 2 Lees 2016" ];
     fhir:RelatedArtifact.citation [ fhir:value "Lees KR, Emberson J, Blackwell L, Bluhmki E, Davis SM, Donnan GA, et al; Stroke Thrombolysis Trialists’ Collaborators Group. Effects of alteplase for acute stroke on the distribution of functional outcomes: a pooled analysis of 9 trials. Stroke. 2016;47:2373-2379. PMID 27507856" ];
     fhir:RelatedArtifact.url [ fhir:value "https://doi.org/10.1161/STROKEAHA.116.013644" ]
  ];
  fhir:EvidenceVariable.actual [ fhir:value "true"^^xsd:boolean];
  fhir:EvidenceVariable.characteristicCombination [ fhir:value "union"];
  fhir:EvidenceVariable.characteristic [
     fhir:index 0;
     fhir:EvidenceVariable.characteristic.definitionReference [
       fhir:link <http://hl7.org/fhir/Group/ECASSIII-Trial-Cohort>;
       fhir:Reference.reference [ fhir:value "Group/ECASSIII-Trial-Cohort" ];
       fhir:Reference.type [ fhir:value "Group" ];
       fhir:Reference.display [ fhir:value "ECASS III Trial Cohort" ]
     ]
  ], [
     fhir:index 1;
     fhir:EvidenceVariable.characteristic.definitionReference [
       fhir:link <http://hl7.org/fhir/Group/IST3-Trial-Cohort>;
       fhir:Reference.reference [ fhir:value "Group/IST3-Trial-Cohort" ];
       fhir:Reference.type [ fhir:value "Group" ];
       fhir:Reference.display [ fhir:value "IST3 Trial Cohort" ]
     ]
  ], [
     fhir:index 2;
     fhir:EvidenceVariable.characteristic.definitionReference [
       fhir:link <http://hl7.org/fhir/Group/ECASS-Trial-Cohort>;
       fhir:Reference.reference [ fhir:value "Group/ECASS-Trial-Cohort" ];
       fhir:Reference.type [ fhir:value "Group" ];
       fhir:Reference.display [ fhir:value "ECASS Trial Cohort" ]
     ]
  ], [
     fhir:index 3;
     fhir:EvidenceVariable.characteristic.definitionReference [
       fhir:link <http://hl7.org/fhir/Group/ECASSII-Trial-Cohort>;
       fhir:Reference.reference [ fhir:value "Group/ECASSII-Trial-Cohort" ];
       fhir:Reference.type [ fhir:value "Group" ];
       fhir:Reference.display [ fhir:value "ECASSII Trial Cohort" ]
     ]
  ], [
     fhir:index 4;
     fhir:EvidenceVariable.characteristic.definitionReference [
       fhir:link <http://hl7.org/fhir/Group/EPITHET-Trial-Cohort>;
       fhir:Reference.reference [ fhir:value "Group/EPITHET-Trial-Cohort" ];
       fhir:Reference.type [ fhir:value "Group" ];
       fhir:Reference.display [ fhir:value "EPITHET Trial Cohort" ]
     ]
  ], [
     fhir:index 5;
     fhir:EvidenceVariable.characteristic.definitionReference [
       fhir:link <http://hl7.org/fhir/Group/ATLANTIS-Trial-Cohort>;
       fhir:Reference.reference [ fhir:value "Group/ATLANTIS-Trial-Cohort" ];
       fhir:Reference.type [ fhir:value "Group" ];
       fhir:Reference.display [ fhir:value "ATLANTIS Trial Cohort" ]
     ]
  ], [
     fhir:index 6;
     fhir:EvidenceVariable.characteristic.definitionReference [
       fhir:link <http://hl7.org/fhir/Group/NINDS-Trial-Cohort>;
       fhir:Reference.reference [ fhir:value "Group/NINDS-Trial-Cohort" ];
       fhir:Reference.type [ fhir:value "Group" ];
       fhir:Reference.display [ fhir:value "NINDS Trial Cohort" ]
     ]
  ] .

<http://hl7.org/fhir/Group/ECASSIII-Trial-Cohort> a fhir:Group .

<http://hl7.org/fhir/Group/IST3-Trial-Cohort> a fhir:Group .

<http://hl7.org/fhir/Group/ECASS-Trial-Cohort> a fhir:Group .

<http://hl7.org/fhir/Group/ECASSII-Trial-Cohort> a fhir:Group .

<http://hl7.org/fhir/Group/EPITHET-Trial-Cohort> a fhir:Group .

<http://hl7.org/fhir/Group/ATLANTIS-Trial-Cohort> a fhir:Group .

<http://hl7.org/fhir/Group/NINDS-Trial-Cohort> a fhir:Group .

# - ontology header ------------------------------------------------------------

<http://hl7.org/fhir/EvidenceVariable/example-Stroke-Thrombolysis-Trialists-2014-2016-IPD-MA-Cohort.ttl> a owl:Ontology;
  owl:imports fhir:fhir.ttl;
  owl:versionIRI <http://build.fhir.org/EvidenceVariable/example-Stroke-Thrombolysis-Trialists-2014-2016-IPD-MA-Cohort.ttl> .

# -------------------------------------------------------------------------------------